منابع مشابه
Endovascular therapy after intravenous t-PA versus t-PA alone for stroke.
BACKGROUND Endovascular therapy is increasingly used after the administration of intravenous tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic stroke, but whether a combined approach is more effective than intravenous t-PA alone is uncertain. METHODS We randomly assigned eligible patients who had received intravenous t-PA within 3 hours after symptom onse...
متن کاملSympathy for stem cells
JCB • VOLUME 172 • NUMBER 5 • 2006 640 T he sympathetic nervous system prepares the body for emergencies. Heart rate and blood pressure rise, pupils dilate, blood is shunted from skin to muscle, and the gut shuts down. Now, Yoshio Katayama, Paul Frenette (Mount Sinai School of Medicine, New York, NY), and colleagues suggest another consequence of sympathetic nervous system activation: hematopoi...
متن کاملتأثیر شش هفته تمرین تناوبی با شدت بالا (HIIT) بر عوامل فیبرینولیتیک (t-PA، PAI-1 و کمپلکس t-PA/PAI-1) مردان جوان غیرفعال
هدف از پژوهش حاضر، بررسی تأثیر شش هفته تمرین تناوبی با شدت بالا (HIIT) بر عوامل فیبرینولیتیک (t-PA، PAI-1 و کمپلکس t-PA/PAI-1) مردان جوان غیرفعال بود. به این منظور، 18 مرد جوان غیرفعال بهصورت داوطلبانه در این پژوهش شرکت کردند و بهطور تصادفی به دو گروه تجربی (9n=، سن:41/1±33/24 سال، قد:91/4±22/176 سانتیمتر، وزن:59/6±27/72 کیلوگرم) و کنترل (9n=، سن:01/2±27/23 سال، قد:88/6±22/180 سانتیمتر، وزن...
متن کاملStent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke.
BACKGROUND Among patients with acute ischemic stroke due to occlusions in the proximal anterior intracranial circulation, less than 40% regain functional independence when treated with intravenous tissue plasminogen activator (t-PA) alone. Thrombectomy with the use of a stent retriever, in addition to intravenous t-PA, increases reperfusion rates and may improve long-term functional outcome. ...
متن کاملGene polymorphism of t-PA is associated with forearm vascular release rate of t-PA.
We have observed marked interindividual differences in release rates of tissue-type plasminogen activator (t-PA) among healthy subjects. The objective of the current study was to test the hypothesis that there is an association between a genetic variation at the t-PA locus and the in vivo release rate of t-PA. Fifty-one healthy males were studied at rest in the morning and 27 of these were also...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2006
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2039iti4